A Randomised Trial of Lymphadenectomy in Patients with Advanced Ovarian Neoplasms
For decades, patients with advanced ovarian cancer have routinely had regional lymph nodes removed; supporting evidence from randomised clinical trials has been limited.
647 patients with ovarian cancer stage IIB through IV and with normal lymph nodes either did or did not undergo lymphadenectomy as a randomised trial.
Lymphadenectomy in patients with advanced ovarian cancer and normal lymph nodes was not associated with longer overall or progression free survival but was associated with a higher surgical mortality and postoperative complications.
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