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Showing posts from September, 2024

Serendipity

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Incidental Findings of Borderline Ovarian  Tumo u r  or Ovarian Cancer -Real-World Data on Surgical and Oncological Outcome https://tinyurl.com/5n8284dj Sometimes ovarian cancer is found by chance during surgical procedures performed for other reasons. The standard of care for such cases is to undergo a repeat surgical procedure at a specialised surgical oncology centre.  This study looks at real-world cases and seeks to determine whether this course of action results in worse outcomes.  This retrospective survey of 390 patients at Bern Hospital  during a 10 - year period from 2010 showed 228 cases of either borderline ovarian  tumour or  ovarian cancer. The outcomes for these women were compared to those  for women who were known to have ovarian cancer prior to single stage surgery at the same centre. Apart from a small delay in starting chemo for those women who has a second operation ,  no  difference in outcomes which include morbidi...

Comorbidity, poisoned soil

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Charlson’s comorbidity and remission outcomes in women diagnosed with epithelial ovarian cancer. https://tinyurl.com/2hmnmvp9 Any surgery carries risk. Complex surgery such as that required for total clearance of o varian cancer has a mortality of  4 % . For some women this risk is increased by pre-existing medical conditions known as comorbidity. This retrospective cohort study seeks to measure the risk inc rease in the presence of comorbidity. Using the Char l son  comorbidity index, which shows associated significant  pre-existing disease as a  risk factor, even the lowest measure at more than 1 significantly decreased the pro s pect of complete  remission  and survival  f rom  ovarian cancer. This means that patients who have one or more other major health issues are less likely to benefit from  intensive primary treatment and that maybe alternative therapy ,  such as maintenance  with personalised car e  should be consider...

AI, the way forward

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LITERARY REVIEW OF ARTIFICIAL INTELLIGENCE IN OVARIAN CANCER: TRANSFORMING DIAGNOSIS, TREATMENT, AND FUTURE ADVANCEMENTS https://tinyurl.com/yc85bx44 Artificial intelligence (AI) has the potential to change the management and improve survival for women with ovarian cancer. This review looks at what is possible now and what may be possible soon in the use of AI for this difficult disease. Increasingly women with ovarian cancer are receiving  personalised  therapy base on the genetic, metabolic, and systemic nature of their cancer. More and more information  caus e  problems  with the understanding of the relevance and interconnection of the data. The great strength of AI is the ability to quickly correlate information and suggest appropriate measures to address the correct therapy path. Using AI for the diagnosis of ovarian cancer will increase the sensitivity and avoid unnecessary intervention in some cases. Increasingly AI is being used for drug research, curre...

Suspicions confirmed

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Differences in cancer rates among adults born between 1920 and 1990 in the USA: an analysis of population-based cancer registry data https://tinyurl.com/wzaxy5w5 Anecdotal experience has suggested that cancer is becoming more common for younger patients. This  suggests that lifestyle changes and environmental effects are causing more cancer. Using data from  population-based cancer registry this study looks at the increase in  cancer risk for younger cohorts. Information is available from this huge study with data from more than  23 million pat ients ,  of whom more than 7 million developed  cancers . Comparing cancer rates from  5-year birth cohorts showed that  for 9 of the 34 different cancers included in the study there was an increase for patients born in the 1990 cohort compared to the 1955 cohort . The mortality has decreased, with better treatment options. Some cancers notably smoking affected cancers such as lung cancer, show a decrease d...