Infertility and ovarian cancer

Assisted reproductive technology and risk of ovarian cancer and borderline tumors in parous women: a population-based cohort study

https://link.springer.com/article/10.1007/s10654-019-00540-3

Assisted reproductive technology (ART) treatments involve systemic use of gonadotropins to stimulate ovarian follicles and subsequent aspiration of ova. ART is suspected to increase the risk of ovarian cancer.

The objective of the study was to investigate the incidence of invasive ovarian cancer and borderline tumours with infertility and ART.

   

The incidence of ovarian cancer was increased in women with infertility and following ART births; (The normal incidence of ovarian cancer is five per thousand women before age 65. This increases to seven for women diagnosed with infertility and eleven following ART). It is statistically significant but the number is small.