Molecular Analysis of Clinically Defined Subsets of High Grade Serous Ovarian Cancer
It has been shown that High Grade Serous Ovarian Cancer has a better outcome when the complete tumour is removed at the time of the initial diagnosis.
This survey looks at the genotype of tumours, which can be completely removed and compares it to the genotype of tumours that require chemotherapy before surgery.
The study finds that patients with cancers that can be completely removed have a different tumour genotype to those patients who required chemotherapy prior to surgery. This suggests that the fact that complete clearance is a good indicator may be in part due to the tumour genotype
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