Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population-based cohort studies and two-sample Mendelian randomization analyses
Data previously obtained from the UK Biobank has shown an association with the consumption of alcohol and a increase in the risk of developing breast cancer, with a less clearly demonstrated possibility of increased risk of ovarian cancer also.
This retrospective study looked at 69000 women from the Copenhagen general population study, all of who consumed more than 10g of alcohol (about one standard drink) daily. Of these women more than 400 subsequently had ovarian cancer and about 4,000, breast cancer.
Hazard ratios for both cancers were obtained with correction for other factors such as obesity and smoking. Drinking alcohol only slightly increases the risk of ovarian cancer. Breast cancer risk increases with consumption of more than two standard drinks daily.
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