Incidence of ovarian cancer after bilateral salpingo-oophorectomy in women with histologically proven endometriosis
Endometriosis cause pain and infertility for many women and also has an increased risk of developing ovarian cancer, with less common types being more frequent for this group of women.
Women with other causes for increased ovarian cancer are encouraged to have risk reduction surgery with removal of the fallopian tubes with or without the ovaries. Because the ovarian cancers associated with endometriosis are less likely to be the typical epithelial type, it was not known if this approach would work for them.
With data from the Dutch Pathology Database this study looked at the ovarian cancer rate for more than 7,000 women with endometriosis after tube removal compared with two control groups; one of 42,000 women with endometriosis without surgery and another group of 132,000 women with no history of endometriosis. It is clear that tube removal is protective for women with endometriosis and in fact reduces the risk of ovarian cancer to less than the normal population.
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