The effect of major postoperative complications on recurrence and long-term survival after cytoreductive surgery for ovarian cancer
Surgery is always an end result of a cost-benefit decision. Will the patient be better or worse after the procedure? This retrospective study looks at the effect on survival for 549 women with ovarian cancer after major postoperative complications.
Recently surgery for ovarian cancer is becoming more aggressive with extended complete resection frequently involving peritoneum and bowel. This debulking surgery may be performed immediately on presentation (PDS), or delayed for either 3 cycles of chemo (IDS), or 6 cycles of chemo (DDS). Patients who have (PDS) are twice as likely to have postoperative complications than those who have DDS.
Postoperative complications have a significant impact on survival. For women who did not have adverse effect following surgery the PFS (Progression Free Survival) and OS (Overall Survival) are 20, and 56 months respectively. Those women who do experience complications have a PFS of 17, and OS, 48 months. Any process of informed consent needs to include details of possible complications.
No comments:
Post a Comment