Once again, the large data base of clinical information in Sweden gives further insight into the epidemiology of ovarian cancer. This study compares the risk of developing ovarian cancer after previous pelvic inflammatory disease. (PID) It is becoming increasingly obvious that infection is an important cause for much cancer.
The retrospective review compared the incidence of PID in 1000 women who developed ovarian cancer with 10000 women who did not have cancer. PID may occur as salpingitis possibly sexually transmitted, be associated with endometriosis, urinary tract infection or inflammatory bowel disease.
Results from the study showed that women with a past history of PID were 39% more likely to develop epithelial ovarian cancer and 46% more likely to develop serous ovarian cancer. The greater the number of PID events the more likely subsequent ovarian cancer occurred.
The authors suggest the increased cancer risk may be due to inflammatory change or persisting bacterial effect and that women with a history of PID should be more actively screened for subsequent ovarian cancer.
No comments:
Post a Comment