Sarcopenia-related Traits, Body Mass Index and Ovarian Cancer Risk: Investigation of Causal Relationships Through Multivariable Mendelian Randomization Analyses
One of the more important changes to medical research has been the start of the UK Biobank. Established in 2015 and now with over 500,000 participants, these volunteers have provided genetic information with full genotyping and general information about health and well-being. On-going data entry is available showing the course of disease in this large group.
This study correlates the development of ovarian cancer with BMI and strength testing together with genetic risk. Obviously with the incidence of ovarian cancer being 7/100,000 each year, the numbers are still small.
However, the early results show that the most significant strength test is the walking speed, (the faster the better), and that BMI in the overweight range is protective. As time passes more information will be obtained from the Biobank. We should all be grateful to those who joined the project.
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