Cannabinoids for adult cancer-related pain: systematic review and meta-analysis
Cannabinoids are naturally occurring compounds found in marijuana. There is a subjective push for the medical use of these substances claiming anti-convulsant, anti-emetic and analgesic properties. Most of these claims do not meet the burden of proof.
This study looked at the available evidence in a meta-analysis of all trials comparing randomised clinical trials of cannabinoids versus placebo using standardised pain intensity measures.
Six trials complied with the criteria, all were deemed to be low bias. There was no demonstrable benefit seen when cannabinoids were added to normal therapy. Adverse effects increased with drowsiness and dizziness.
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