The Effect of Delayed Chemotherapy on the Decrease of CA125 in Epithelial Ovarian Cancer During Coronavirus Disease Pandemic in 2020
The global pandemic of 2020, has been dreadful, some of the effects are as yet unclear. One certain result is that normal treatment of ovarian cancer has been adversely affected. Unlike other cancers there is a readily available measure of the effectiveness of treatment; this is the serum measure of the protein antigen CA125.
A good sign of the effectiveness of primary treatment, including surgery and chemo, is that the serum CA125 level returns to the normal range.
Because of the risk of the pandemic chemo has been delayed for many ovarian cancer patients. This study looked at 32 women with ovarian cancer who had delay in chemo of up to 60 days. Despite this the half-life time of the CA125 was unaffected in this group when compared to a similar pre pandemic group. Obviously the follow up time is short but thus far the survival is unaffected by the delay.
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