Role of pre-diagnostic reproductive factors on long-term (10 years or greater) survival of epithelial ovarian cancer: The Extreme study
It is well known that the risk of ovarian cancer is reduced by reproductive factors such as, previous pregnancy, breast feeding, and oral contraception.
This retrospective study, using information from the Danish health system, looks at survival after ovarian cancer for almost 12,000 women and sought to relate the chance of survival to previous gynaecological history.
Results from the study suggest that a previous history of childbirth, endometriosis, and infertility are protective with between 8% and 17% better survival respectively.
A history of previous hysterectomy or salpingectomy showed no survival benefit. The authors make no suggestion as to why this is so but suggest further research may be indicated.
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