Is endometriosis a significant cancer risk?

Endometriosis and ovarian cancer risk

https://tinyurl.com/36vyrxjf

Endometriosis is a chronic cause of pain for about 10% of women during their reproductive life. The cause remains uncertain; initially thought to result from retrograde menstruation, the implanted cells found throughout the pelvis, which have a similar appearance to the uterine epithelium, may be due to stem cell activation.

Chronic inflammation from endometriosis has been cited as a possible cause for ovarian cancer. This study, looking at all available information using a standard methodology known as the PRISMA guidelines, suggests that the risk is low for most types of ovarian cancer, although there is an increased risk of endometrioid and clear cell cancer, which account for about 10% of the total.

Because ovarian cancer generally has a low incidence, with about 11/1000 women developing the disease during their lifetime, the overall risk increase due to endometriosis at about 1.3 means a small number of 3-4 extra cases. Because of this, the authors suggest that women with endometriosis should be reassured that ovarian cancer is unlikely, and extra surveillance is not indicated.