Sedentary behaviour in relation to ovarian cancer risk: a systematic review and meta-analysis
Inactivity is a health hazard. As a potential risk factor for ovarian cancer, which can be modified, there is little understanding of the increased risk due to a sedentary lifestyle.
Databases at PubMed and Web of Science were accessed and seven studies had suitable data for meta-analysis, with information for just over 2000 women with ovarian cancer.
Retrospective analysis of the data shows an increase in the relative risk of ovarian cancer to 1.29 due to prolonged sitting. This relates to an increase of approximately 3 cases/100,000 women in Australia, each year.
Sedentary behaviour is defined as spending more than half of waking hours sitting or reclining. Interestingly this does not necessarily imply a lack of exercise, as the usual recommendations of physical activity can be completed and still have a sedentary lifestyle.
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