Co-existence of breast and ovarian cancers in BRCA germ-line mutation carriers
Mutation of the BRCA genes is known to predispose to women having either breast or ovarian cancer, sometimes both. There is limited previous information about the cause and effect of synchronous breast and ovarian cancers, one study suggesting about two thirds of those women affected are BRCA positive.*
This small retrospective study looks at 6 women with both cancers, with greater detail about one case suggesting the possibility that the ovarian cancer could be a distant metastasis of a primary breast cancer.
It is apparent that women unfortunate enough to have both ovarian cancer and breast cancer during their lifetime should prompt genetic screening of close relatives.
* https://tinyurl.com/msn2jybr
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